Our research is focused on developing optofluidic techniques to solve the problems in biomedical research.
We are particularly interested in:
Novel optothermal tweezers
Relevant Publications:
- Cong, H., Loo, F. C., Chen, J.*, et al. (2019). Target trapping in situ single cell genetic marker detection with a focused optical beam. Biosensors and Bioelectronics, 133, 236-242. (corresponding author).
- Cong, H, Chen J.*, and Ho H. P. (2018) Trapping, sorting and transferring of micro-particles and live cells using electric current-induced thermal tweezers. Sensors and Actuators B: Chemical, 264: 224-233. (corresponding author).
- Chen, J., Cong, H., Loo F. C., et al. (2016). Thermal gradient induced tweezers for particles and cells manipulation, Scientific reports, 6, 35814.
- Chen, J., Kang, Z., Lu, H., et al. (2015). Photochemically synthesized silver nanostructures on tapered fiber as plasmonic tweezers for surface enhanced Raman scattering applications, Vacuum, 118, 171-176. (Cover paper)
- Chen, J., Kang Z., Wang, G., et al. (2015). Optofluidic guiding, valving, switching and mixing based on plasmonic heating in random gold nanoisland substrate, Lab on a Chip, 15(11), 2504-2512.
- Chen, J., Kang, Z., Ho, H. (2015). Gold film coated fiber tip for trapping live cells and nanoparticles, Optics letters, 40(17), 3926-3929.
- Kang, Z., Chen, J., & Ho, H. P. (2016). Surface-enhanced Raman scattering via entrapment of colloidal plasmonic nanocrystals by laser generated microbubble on random gold nano-islands, Nanoscale, 8(19), 10266-10272.
- Kang, Z., Chen, J., Wu, S. Y., & Ho, H. P. (2015). Plasmonic absorption activated trapping and assembling of colloidal crystals with non-resonant continuous gold films, RSC Advances, 5(127), 105409-105415.
- Kang，Z., Chen J., Wu S., et al. (2015). Trapping and assembling of particles and live cells on large-scale random gold nano-island substrates, Scientific reports, 5, 9978.
- Kang, Z., Lu, H., Chen, J., Chen, K., Xu, F., & Ho, H. P. (2014). Plasmonic graded nano-disks as nano-optical conveyor belt. Optics express, 22(16), 19567-19572.
- Lu, H., Ren, X., Wei, E. I., Chen, J., et al. (2015). Experimental and Theoretical Investigation of Macro-Periodic and Micro-Random Nanostructures with Simultaneously Spatial Translational Symmetry and Long-Range Order Breaking, Scientific reports, 5, 7876.
Enhanced surface plasmon resonance imaging
Relevant Publications:
- Chen, J., Zeng, Y., Zhou, J., Wang, X., Jia, B., Miyan, R., ... & Gu, Y. (2022). Optothermophoretic flipping method for biomolecule interaction enhancement. Biosensors and Bioelectronics, 114084.
- Zhou, J., Wang, X., Chen, J., Zeng, Y., Gu, D., Gao, B. Z., & Shao, Y. (2022). Polymeric microsphere enhanced surface plasmon resonance imaging immunosensor for occult blood monitoring. Sensors and Actuators B: Chemical, 350, 130858.
- Wang, M., Chen, J., Wang, L., Zheng, X., Zhou, J., Zeng, Y., ... & Gao, B. Z. (2021). Recent Progress in the Correlative Structured Illumination Microscopy. Chemosensors, 9(12), 364.
- Miyan, R., Wang, X., Zhou, J., Zeng, Y., Qu, J., Ho, H. P., ... & Shao, Y. (2021). Phase interrogation surface plasmon resonance hyperspectral imaging sensor for multi-channel high-throughput detection. Optics Express, 29(20), 31418-31425.
- Chen, X., Waller, L., Chen, J., Tang, R., Zhang, Z., Gagne, I., ... & Lo, Y. H. (2021). Label-free image-encoded microfluidic cell sorter with a scanning Bessel beam. Apl Photonics, 6(7), 076101. (corresponding author).
- Wang, M., Wang, L., Zheng, X., Zhou, J., Chen, J., Zeng, Y., ... & Gao, B. Z. (2021). Nonlinear scanning structured illumination microscopy based on nonsinusoidal modulation. Journal of Innovative Optical Health Sciences, 2142002. (corresponding author).
- Wang, X., Zeng, Y., Zhou, J., Chen, J.*, Miyan, R., Zhang, H., ... & Shao, Y.* (2020). Ultrafast Surface Plasmon Resonance Imaging Sensor via the High-Precision Four-Parameter-Based Spectral Curve Readjusting Method. Analytical Chemistry, 2021, 93 (2): 828-833. (corresponding author).
- Zheng, X. , Li, X. , Lin, Q. , Chen, J. * , & Shao, Y. * (2020). Multi-laser scanning confocal fluorescent endoscopy scheme for subcellular imaging. Progress In Electromagnetics Research, 169, 17-23. (corresponding author).
- Zeng, Y., Wang, X., Zhou, J., Miyan, R., Qu, J., Ho, H. P., Chen, J.*& Shao, Y.* (2020). High-throughput imaging surface plasmon resonance biosensing based on ultrafast two-point spectral-dip tracking scheme. Optics Express, 28(14), 20624-20633. (corresponding author).
- Chen, J., Loo, J. F. C., Wang, D., Zhang, Y., Kong, S. K., & Ho, H. P. (2020). Thermal optofluidics: principles and applications. Advanced Optical Materials, 8(1), 1900829.